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By 2050, a seismic demographic shift will unfold as 16% of the global population, an astounding 1.3 billion people, are predicted to reach the age of 65 or older. The effect of an ageing population is already having a dramatic impact on healthcare systems which are stretched in many countries. Innovative solutions abound from gene therapies to personalised care plans but some areas of the market face headwinds and risk. We reveal the specific parts of the market that we favour, and the reasons why we invest in the companies we do.

Source: Analysis of linked healthcare records and mortality data conducted by the REAL Centre and the University of Liverpool.
That chart above clearly highlights the stark reality of an ageing population and the healthcare challenges we face. The huge increase in need and future demand, however, is also an opportunity that’s incentivising innovative companies to develop new products and services. And these will be radically beneficial for patients, with more effective treatments for major illnesses already in the pipeline. Care delivery is also transforming, with advances in efficiency and availability allowing people to receive treatment from the comfort of their own home rather than going to hospital as they do now.
Healthcare markets are complex and cover everything from pharmaceuticals and biotechnology to medical technology and the life science tools required for research, testing and product manufacturing. That’s why a clear focus on identifying the specific segments exposed to long-term growth trends makes sense, and fundamental analysis is necessary to identify the highest-quality companies that we believe will be able to deliver an attractive return on capital over our investment horizon of 5-10 years.
Following our analysis, our highest conviction lies in companies positioned in one of two categories: technology and more efficient means of delivering care. On the other hand, our view is that the more traditional pharmaceutical companies face many more challenges and external risks that could negatively impact their future earnings.
Fortunately, groundbreaking technological advancements, particularly in genomics (the branch of biology that focuses on DNA mapping and editing) are poised to alleviate some of the strain on care providers and have the potential to revolutionise patient care offering higher quality, personalised treatment options.

For example, we have invested in Illumina, the global leader for next-generation genetic testing and analysis. Their pioneering technology has become indispensable in this field, making advanced testing more accessible and affordable across various sectors. Illumina's comprehensive hardware and software ecosystem streamline the entire sequencing process, empowering industry professionals like researchers and bioinformaticians to enhance their work within an integrated platform.
In our view, another standout in the medical technology sector is Sartorius Stedim, a leading provider in the single-use bioprocessing (SUT) market. Catering to pharmaceutical, biotechnology, and contract drug development firms, Sartorius Stedim's equipment and consumables support the manufacturing of biologic, cell, and gene therapy (CGT) drugs. They enable smaller batch production, reduce upfront costs, and enhance operational efficiency, addressing the evolving needs of these rapidly growing drug types.
Mettler-Toledo gives us exposure to similar themes, as the leading global supplier of mission-critical precision balance instruments and services for life science (largely pharma), industrial and food industries. Veeva Systems, meanwhile, provides industry-tailored software as a service (SaaS), aiding biopharma clients in drug development applications, enhancing customer efficiency and streamlining processes.
The inside story on the leading companies in our global portfolio and why they offer sustainable, long-term growth potential.
As technology advances, we are also impressed by some improvements in healthcare delivery, ensuring that patients can conveniently access services at their preferred time and location, at a lower cost to the care provider.
One leading player we have invested in is ResMed. It offers cloud-connected devices and software to treat breathing conditions like sleep apnea and chronic obstructive pulmonary disorder (COPD), which are often lifestyle-driven diseases (obesity and smoking, respectively). The technology enables patients to receive care at home under medical supervision, reducing hospitalization costs and capacity strain.
Coloplast sells disposable chronic care products primarily to treat ostomates and patients needing continence care, often due to age-related cancers. These products help patients regain and enhance their quality of life while also saving healthcare costs by transitioning care from hospitals to home settings.
We are less positive on the major drug-producing pharmaceutical and biotechnology firms. They are exposed to more risks that could potentially limit their earnings power and make accurately forecasting their future complicated. These include various regulatory challenges and increased risk of litigation because of product safety concerns or unintended side effects. They are also attracting increasing political scrutiny because of strong historical price increases for limited innovation. In the US, this has resulted in the introduction of the Inflation Reduction Act, which brings direct price controls on drugs sold under Medicare.
The perception that pharmaceutical prices are rising is misleading, however, as net prices have in fact decreased by 3% annually over the past five years (after intermediary rebates)1. This trend is expected to worsen. Research and development has become narrowly focused on some common illnesses are areas like oncology, intensifying competition and negatively impacting the industry economics.
That said, we do see potential in speciality pharma and animal health sectors. For example, CSL is as a leading player in biopharmaceuticals, benefiting from regulatory protection in the blood plasma therapeutics business due to historical safety concerns. This barrier to entry reduces patent risks and reimbursement pressures, making the market more attractive.
In the animal health sector, Zoetis and Idexx Laboratories are major players with significant market shares in animal drug and diagnostic markets vital for livestock and pet markets. Compared to traditional human pharma, animal health research is still developing, offering higher returns on research investment with fewer regulatory hurdles - and less competition. This leads to longer product cycles and a more stable pricing environment post-patent expiration, characteristics that we like.
In conclusion, demographics and lifestyle trends are fuelling sustained demand for healthcare innovation and efficiency. Many companies in this sector offer promising growth prospects, shielded from disruption by regulatory barriers with specialised expertise. Martin Currie Global Portfolio Trust capitalises on these opportunities by investing in firms with strong growth potential and high return on invested capital. We currently have over 20% of the portfolio invested in healthcare-related companies, making it one the Trust’s largest exposures.
This highlights our belief in the sector’s ongoing ability to meet ongoing challenge while delivering healthy returns for investors.
1 Source: Drugchannels.net and Martin Currie, December 2023
The information provided should not be considered a recommendation to purchase or sell any particular security. It should not be assumed that any of the security transactions discussed here were or will prove to be profitable. These opinions are not intended to be a forecast of future events, research, a guarantee of future results or investment advice.
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